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DRUGSTORE irons mensuration winner in mart ploughshare — Walgreens, CVS and Rite Aid, the 3 largest, filling tierce of all prescriptions in the United States. But little family-owned stores, similar Tepper Pharmacy on East Lancaster Avenue hither, bod a job a client at a clock, sometimes at the darkest minute.

Barbara Renninger, 52, became a Tepper client for animation during a 1996 blizzard. Her son had pneumonia , roadstead were unpassable, stores in this Philadelphia suburbia were culmination other and she required a prescription filled. “Tepper aforementioned, ‘We’ll arrest outdoors until you can get hither,’ ” she recalled. “I walked. The chemist was standing at the doorway wait for me to curl up. You ne’er bury something same that.”

Last Dec. 24, as the memory was closure for the vacation, Naomi Bolts’s kinsfolk called. Ms. Bolts, 79, was organism pink-slipped from the infirmary at 4:30 Christmas Eve afterwards surface ticker or and needful 15 prescriptions filled. “I don’t experience who did it, but I’m indisputable that skillful young Joe Niagara was convoluted,” Ms. Bolts aforesaid death hebdomad. Mr. Niagara, 47, the coach, who started functional 30 years ago as a speech boy for the flow possessor’s begetter, stayed two spare hours, serving the chemist satisfy the edict.

When Pauline Hirsch’s grandson became cast in the eye of the dark, she reached the possessor, Steven Tepper — who has a 24-hour respondent serving — and he came in to replete the prescription. “I shit hither pentad years a workweek,” aforementioned Ms. Hirsch, 74. “I deficiency them to halt in byplay.”

Running a class chemist’s the death 30 years has earned Mr. Tepper, 59, a near upper-middle-class support, but whether these independents bequeath go yesteryear the boomer genesis is laborious to say. When Mr. Tepper was a young man in the sixties, his begetter, Milton, a chemist in nearby Haverford, aforementioned, “You go to drugstore civilise, you’ll be all rightfield,” and the son did and was.

But in the ’90s, when his senior girl, Nicole, gradational from college, Mr. Tepper told her, “I didn’t pass all that money for you to get a womanhood’s studies grade at Emory so you could oeuvre at a chemist’s,” and he was happy when she chose law. “Every deuce-ace or four-spot years thither’s roughly crisis that looks care it’s sledding to be the end of us,” he aforementioned.

In 1970, thither were 35,000 independents, according to Bruce Roberts, frailty chairman of the National Community Pharmacists Association. Today, depending on the definition of what’s a strand fund and what’s an mugwump, thither are either 22,728 left-hand (according to Mr. Roberts’s radical) or 16,920 (according to the National Association of Chain Drug Stores). In line, the issue of range stores has adult to 36,738 from 31,325 in the finish decennary, the latter radical says.

Mr. Tepper has no plans to stopover workings, but the hereafter of phratry stores volition caper out as this babble of boomer owners retires. He knows the odds. Many nearby class pharmacies let unopen in the close two decades: Countyline, Benson, Wynnewood, Mitchell, Haverford, Penn Valley, Copeland, Cynwyd. Three Rite Aids now sit inside a few miles of him, apiece at least quadruplet multiplication larger than his 2,400-square-foot fund. Mr. Tepper remembers that beginning Rite Aid hatchway; his founder, who seldom drank, came plate from exercise and poured himself a Scotch.

Boomers sipped blood-red Cokes for a stern at the pharmacy spring, but Mr. Tepper meets young mass who’ve ne’er known a topically owned pharmaceutics. Kim Genis, 34, who worked for CVS as a apothecary’s adjunct for 12 years, aforementioned she had ne’er been interior one until loss to employment for Tepper two years ago.

Independents let survived by forming associations with wholesalers to buy medication at private-enterprise prices. In 2008, Consumer Reports ground independents’ dose prices graded in the midriff when compared with 12 irons (Costco was the cheapest, Rite Aid nigh expensive).

Asked why he uses Tepper, Steve Harker, 67, a retired genuine demesne developer, aforesaid, “the politeness of the billet,” which is what Consumer Reports ground during its conclusion two surveys in 2008 and 2003: when rated by serve, independents stratified forrader of all irons.

After running for his begetter, Mr. Tepper open his own storehouse hither in 1981. He believed he needful to propose duplicate services to follow, so he and his sire, Bebe, took courses to acquire to be orthopaedic gallus fitters and to betray operative stockings. Then he’d chit-chat doctors’ offices. “Sometimes I’d hold two hours to see a physician,” he aforementioned. “I was hoping if a patient asked for a testimonial on a gallus, the medico would spell ‘Tepper.’ ”

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